Scope of Guidance
Terms and Definitions
Introduction
Legal Duty
Exposure Risk and Hazardous Properties of Nanomaterials
Risk Management Principles
Nanomaterials’ Characterisation
Background and challenges
Selection of properties and techniques for characterisation
Toxicology
Hazard Information
Hazard Banding
Exposure Control
Risk Assessment
Prevention and control of exposure
Prevention of exposure: Substitution
Workplace Exposure Limits
Approaches to selecting control measures
Control of exposure to particulate nanomaterials
Inhalation risk
Dermal and ingestion risk
Engineering Control Measures
HEPA Filtration Efficiency
Local Exhaust Ventilation (LEV)
Ducted Microbiological Safety Cabinets (MSCs)
Ductless re-circulating HEPA-filtered containment cabinets and re-circulating MSCs
Maintenance, examination and testing of control measures
Personal Protective Equipment (PPE)
Eye protection
Respiratory protective equipment
Gloves
Protective
Protective clothing
Cleaning spillages
Specific Advice for High Aspect Ratio Nanomaterials (HARNs)
Information, Instruction and Training
Monitoring
Limitations to monitoring
Instruments used
Sampling strategy
Limitations
Health Surveillance
Disposal of Waste Nanomaterials
Preparation of nanomaterial waste prior to disposal
Disposal by waste contractors
Labelling and Signs
References
APPENDIX 1: Comparison of US Microbiological Safety Cabinet characteristics and applicability for nanomaterials
APPENDIX 2: Particulate Nano-Material Control Measures Selection Flowchart
APPENDIX 3: Engineering Controls
APPENDIX 4: Record of Work Activity Form
APPENDIX 5: Sampling Protocol to assess release of particulate nanomaterials to the air