Inhalation Toxicity Testing: Expert Meeting on Potential Revisions to OECD Test Guidelines and Guidance Document

Publication Date : 2012
Code : 104
178 Visited Entry Date : 2017/10/02

International

English
Volume 35 Pages
Document type Event Report
Subject Characterization & Testing
Summary

The expert meeting on Inhalation Toxicity Testing for Nanomaterials was held on 19-20 October 2011 in The Hague, hosted by the Netherlands, with the aim of discussing the results of the OECD Sponsorship Programme (under the responsibility of SG3) on this specific topic and addressing issues relevant to inhalation toxicity. Fifty experts from the WPMN as well as the OECD Working Group of the National Coordinators for the Test Guidelines programme (WNT) participated in the meeting. This document is the meeting report.

This document includes summaries and recommendations from each of the presentations (Annex II) as well as suggested revisions to the OECD Test Guidelines (TGs 403, TG412, TG413 and TG436), the Guidance Document on Acute Inhalation Toxicity Testing and the Preliminary Guidance Notes on Sample Preparation and Dosimetry for the Safety Testing of Manufactured Nanomaterials. It also includes the meeting agenda (Annex I), and the Participants list (Annex III).
Content

ABOUT THE OECD

 

FOREWORD

 

OECD’S PROGRAMME ON THE SAFETY OF MANUFACTURED NANOMATERIALS

 

EXECUTIVE SUMMARY

 

REPORT OF THE WPMN EXPERT MEETING ON INHALATION TOXICITY TESTING FOR NANOMATERIALS

   Summary    

   Objectives of the Workshop    

   Recommendations raised by the speakers for the discussion    

   Discussions among all participants    

 

ANNEX I: MEETING AGENDA

 

ANNEX II: SUMMARY OF PRESENTATIONS

   Session 1 - General Presentations: Setting the Scene    

   Session 2 - Contributions by inhalation experts from the OECD Sponsorship Programme    

   Session 3 - Studies on Inhalation Toxicity    

 

ANNEX III: PARTICIPANTS LIST

 

ANNEX IV: SUGGESTED REVISION FOR THE OECD TEST GUIDELINES AND GUIDANCE DOCUMENTS

   Suggested revision for OECD Test Guidelines and Guidance Documents Drafted by Hans Muijser (TNO Triskelion bv) and Flemming R. Cassee (RIVM)    

      A. TG 403/412/413/436 on Inhalation Toxicity in light of the use for testing nanomaterials         

      B. ENV/JM/MONO(2009)28 Guidance Document on Acute Inhalation Toxicity Testing         

      C. ENV/JM/MONO(2010)25 Preliminary Guidance Notes on Sample Preparation and Dosimetry for the Safety Testing of Manufactured Nanomaterials          
Organization
  • Organisation for Economic Co-operation and Development Published by
  • Inter-Organisation Programme for the Sound Management of Chemicals Supported by
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